Human (GRCh38.p14)
Description

B-Raf proto-oncogene, serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:1097]

Gene Synonyms

BRAF-1, BRAF1

About this transcript

This transcript has 18 exons, is annotated with 250 domains and features, is associated with 90105 variant alleles and maps to 662 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000646891.2BRAF-2206459766aaENSP00000493543.1
 
Protein coding
CCDS5863P15056 NM_004333.6MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P4
ENST00000644969.2BRAF-2159807807aaENSP00000496776.1
 
Protein coding
CCDS94219A0A2R8Y8E0 NM_001374258.1MANE Plus ClinicalGENCODE basic
ENST00000496384.7BRAF-2049578767aaENSP00000419060.2
 
Protein coding
CCDS87555H7C560 -GENCODE basicAPPRIS ALT1TSL:5
ENST00000288602.11BRAF-2012561806aaENSP00000288602.7
 
Protein coding
CCDS94218A0A2U3TZI2 -GENCODE basicTSL:1
ENST00000469930.2BRAF-2021180172aaENSP00000495858.1
 
Protein coding
A0A2R8YES9 -GENCODE basicTSL:2
ENST00000646730.1BRAF-2192829584aaENSP00000494784.1
 
Nonsense mediated decay
A0A2R8YDP5 --
ENST00000642228.1BRAF-2062574300aaENSP00000493678.1
 
Nonsense mediated decay
A0A2R8Y467 --
ENST00000497784.2BRAF-2052387209aaENSP00000420119.2
 
Nonsense mediated decay
H7C5K3 -TSL:5
ENST00000644650.1BRAF-2131639411aaENSP00000493783.1
 
Nonsense mediated decay
A0A2R8Y492 -CDS 5' incomplete
ENST00000647434.1BRAF-2211217274aaENSP00000495132.1
 
Nonsense mediated decay
A0A2R8Y679 -CDS 5' incomplete
ENST00000479537.6BRAF-2031129231aaENSP00000418033.2
 
Nonsense mediated decay
H7C4S5 -TSL:5CDS 5' incomplete
ENST00000644120.1BRAF-2123889No protein-
 
Protein coding CDS not defined
---
ENST00000643790.1BRAF-211575No protein-
 
Protein coding CDS not defined
---
ENST00000642808.1BRAF-208439No protein-
 
Protein coding CDS not defined
---
ENST00000644905.1BRAF-2145217No protein-
 
Retained intron
---
ENST00000642875.1BRAF-2092871No protein-
 
Retained intron
---
ENST00000642272.1BRAF-2072320No protein-
 
Retained intron
---
ENST00000646427.1BRAF-2182265No protein-
 
Retained intron
---
ENST00000645443.1BRAF-2162190No protein-
 
Retained intron
---
ENST00000646334.1BRAF-2171779No protein-
 
Retained intron
---
ENST00000643356.1BRAF-210853No protein-
 
Retained intron
---
Statistics

Exons: 18, Coding exons: 18, Transcript length: 6,459 bps, Translation length: 766 residues

MANE

This MANE Select transcript contains ENSP00000493543 and matches to NM_004333.6 and NP_004324.2

Uniprot

This transcript corresponds to the following Uniprot identifiers: P15056

CCDS

This transcript is a member of the Human CCDS set: CCDS5863

Version

ENST00000646891.2

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.