Human (GRCh38.p14)
Description

glutamate-cysteine ligase catalytic subunit [Source:HGNC Symbol;Acc:HGNC:4311]

Gene Synonyms

GCS, GLCL, GLCLC

Location
About this transcript

This transcript has 15 exons, is annotated with 8 domains and features, is associated with 19007 variant alleles and maps to 653 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000650454.1GCLC-2143785637aaENSP00000497574.1
 
Protein coding
CCDS4952P48506 Q14TF0 NM_001498.4MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P1
ENST00000509541.5GCLC-2053774361aaENSP00000495056.1
 
Protein coding
A0A2R8Y648 -GENCODE basicTSL:5
ENST00000616923.5GCLC-2123287584aaENSP00000482756.2
 
Protein coding
B4E2I4 -GENCODE basicTSL:1
ENST00000514004.5GCLC-2082356252aaENSP00000421908.1
 
Protein coding
A0A0C4DGB2 -GENCODE basicTSL:1
ENST00000643939.1GCLC-2132289639aaENSP00000495686.1
 
Protein coding
A0A2R8YEL6 -CDS 5' incomplete
ENST00000513939.6GCLC-2071800599aaENSP00000424211.2
 
Protein coding
CCDS75471E1CEI4 -GENCODE basicTSL:2
ENST00000505197.1GCLC-20359218aaENSP00000427403.1
 
Protein coding
D6RIT4 -TSL:4CDS 3' incomplete
ENST00000504525.1GCLC-202101154aaENSP00000421228.1
 
Nonsense mediated decay
D6RGF8 -TSL:3
ENST00000514933.2GCLC-210553No protein-
 
Protein coding CDS not defined
--TSL:5
ENST00000515580.1GCLC-2112132No protein-
 
Retained intron
--TSL:1
ENST00000505294.5GCLC-204847No protein-
 
Retained intron
--TSL:3
ENST00000510837.5GCLC-206776No protein-
 
Retained intron
--TSL:2
ENST00000504353.1GCLC-201597No protein-
 
Retained intron
--TSL:3
ENST00000514373.3GCLC-209332No protein-
 
Retained intron
--TSL:2
Statistics

Exons: 15, Coding exons: 15, Transcript length: 1,800 bps, Translation length: 599 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS75471

Transcript Support Level (TSL)

TSL:2

Version

ENST00000513939.6

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.