Description
Conserved peptide N-glycanase; deglycosylating enzyme that cleaves N-glycans that are attached to misfolded ERAD substrate glycoproteins prior to proteasome-dependent degradation; localizes to the cytoplasm and nucleus; activity is enhanced by interaction with Rad23p; human ortholog NGLY1 is associated with a syndrome characterized by developmental delays, epilepsy, absence of tears and liver disease [Source:SGD;Acc:S000006017]
Location
Chromosome XVI: 366,927-368,018 forward strand.
R64-1-1:BK006949.2
About this gene
This gene has 1 transcript (splice variant) and 214 orthologues.
Transcripts
