Description
Seipin involved in lipid droplet (LD) assembly; controls lipid particle morphology, number, and size; promotes initiation of LD formation on the ER; ensures that LDs bud from the ER towards the cytosolic side of the membrane; forms a complex with Ldb16p at ER-LD contact sites, stabilizing these sites; null mutants have localized accumulation of phosphatidic acid (PA) marker proteins; BSCL2, human homolog implicated in congenital lipodystrophy, complements yeast null mutant [Source:SGD;Acc:S000004396]
Location
Chromosome XII: 928,743-929,600 forward strand.
R64-1-1:BK006945.2
About this gene
This gene has 1 transcript (splice variant).
Transcripts
