DEAH-box RNA helicase involved in second catalytic step of splicing and in exon ligation; exhibits ATP-dependent RNA unwinding activity; mediates the release of Yju2p and Cwc25p in the second step; in the absence of ATP, stabilizes the binding of Cwc25p to the spliceosome in the first catalytic step; missense mutation in human ortholog DHX38 associated with early-onset retinitis pigmentosa [Source:SGD;Acc:S000001794]
PRP23, RNA16
Chromosome XI: 599,857-603,072 forward strand.
R64-1-1:BK006944.2
This gene has 1 transcript (splice variant), 205 orthologues and 6 paralogues.