Description
S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]
Gene Synonyms
SLI2
Location
Chromosome XI: 205,707-207,749 forward strand.
R64-1-1:BK006944.2
About this gene
This gene has 1 transcript (splice variant), 1 orthologue and 1 paralogue.
Transcripts
