Nuclear polyadenylated RNA-binding protein; required for nuclear mRNA export and poly(A) tail length control; stimulates RNA polymerase III transcription by enhancing TFIIIB binding to promoters; protects mRNA against decay by the nuclear exosome in a poly(A)-tail-dependent manner; involved in forming export-competent mRNPs in the nucleus; autoregulates mRNA levels; NLS binds Kap104p; protein abundance increases under DNA replication stress; related to human hnRNPs [Source:SGD;Acc:S000003090]
Chromosome VII: 278,946-280,523 reverse strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant) and 214 orthologues.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YGL122C_mRNA | NAB2 | 1578 | 525aa | YGL122C | Protein coding | P32505 | Ensembl Canonical, |