Inositol phosphosphingolipid phospholipase C; mitochondrial membrane localized; hydrolyzes complex sphingolipids to produce ceramide; activates genes required for non-fermentable carbon source metabolism during diauxic shift; activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol; mediates Na+ and Li+ halotolerance; ortholog of mammalian neutral sphingomyelinase type 2 [Source:SGD;Acc:S000000821]
Chromosome V: 192,797-194,230 forward strand.
R64-1-1:BK006939.2
This gene has 1 transcript (splice variant) and 200 orthologues.