Description
RNA-binding protein; promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; represses translation initiation by binding eIF4G; required for pre-mRNA splicing; interacts with E3 ubiquitin ligase Bre1p, linking histone ubiquitination to mRNA processing; may have role in telomere maintenance; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in cytoplasm; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000002840]
Gene Synonyms
MTR13, MTS1, NAB1, NOP3
Location
Chromosome IV: 1,328,783-1,330,027 forward strand.
R64-1-1:BK006938.2
About this gene
This gene has 1 transcript (splice variant).
Transcripts
