Description
Glutathione-dependent oxidoreductase; hydroperoxide and superoxide-radical responsive; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage; with Grx4p, binds to Aft1p in iron-replete conditions, promoting its dissociation from promoters; evidence exists indicating that the translation start site is not Met1 as currently annotated, but rather Met36; GRX3 has a paralog, GRX4, that arose from the whole genome duplication [Source:SGD;Acc:S000002505]
Location
Chromosome IV: 644,178-644,930 reverse strand.
R64-1-1:BK006938.2
About this gene
This gene has 1 transcript (splice variant), 224 orthologues and 2 paralogues.
Transcripts
