Description
S-phase checkpoint protein required for DNA replication; couples DNA helicase and polymerase; interacts with and stabilizes Pol2p at stalled replication forks during stress, where it forms a pausing complex with Tof1p and is phosphorylated by Mec1p; defines a novel S-phase checkpoint with Hog1p that coordinates DNA replication and transcription upon osmostress; protects uncapped telomeres; Dia2p-dependent degradation mediates checkpoint recovery; mammalian claspin homolog [Source:SGD;Acc:S000000566]
Gene Synonyms
YCL060C
Location
Chromosome III: 18,816-22,106 reverse strand.
R64-1-1:BK006937.2
About this gene
This gene has 1 transcript (splice variant).
Transcripts
