Transcript: ENST00000392870.3 GRK5-202

Description

G protein-coupled receptor kinase 5 [Source:HGNC Symbol;Acc:HGNC:4544]

Gene Synonyms

GPRK5

Location

Chromosome 10: 119,207,571-119,459,745 forward strand.

About this transcript

This transcript has 16 exons, is annotated with 32 domains and features, is associated with 109234 variant alleles and maps to 863 oligo probes.

Gene

This transcript is a product of gene ENSG00000198873.12 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000392870.3	GRK5-202	6798	590aa	ENSP00000376609.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS7612	P34947	NM_005308.3	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENST00000369108.4	GRK5-201	5267	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,

Summary

Statistics

Exons: 16, Coding exons: 16, Transcript length: 6,798 bps, Translation length: 590 residues

MANE

This MANE Select transcript contains ENSP00000376609 and matches to NM_005308.3 and NP_005299.1

Uniprot

This transcript corresponds to the following Uniprot identifiers: P34947

CCDS

This transcript is a member of the Human CCDS set: CCDS7612

Transcript Support Level (TSL)

TSL:1

Version

ENST00000392870.3

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript: ENST00000392870.3 GRK5-202

Summary

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Transcript: ENST00000392870.3 GRK5-202

Summary

About Us

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