Human (GRCh38.p14)
Description

aph-1 homolog B, gamma-secretase subunit [Source:HGNC Symbol;Acc:HGNC:24080]

Gene Synonyms

APH-1B, DKFZP564D0372, PSFL

Location
About this transcript

This transcript has 5 exons, is annotated with 12 domains and features, is associated with 11891 variant alleles and maps to 201 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000261879.10APH1B-2014138257aaENSP00000261879.5
 
Protein coding
CCDS10184Q8WW43-1 NM_031301.4MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P1TSL:1
ENST00000560890.5APH1B-210758188aaENSP00000453002.1
 
Protein coding
H0YKZ9 -TSL:3CDS 3' incomplete
ENST00000380343.8APH1B-203685216aaENSP00000369700.4
 
Protein coding
CCDS45276Q8WW43-2 -GENCODE basicTSL:1
ENST00000560353.1APH1B-208672222aaENSP00000453327.1
 
Protein coding
H0YLT0 -TSL:3CDS 3' incomplete
ENST00000559971.5APH1B-207145519aaENSP00000453516.1
 
Nonsense mediated decay
H0YM95 -TSL:1CDS 5' incomplete
ENST00000380340.8APH1B-20287281aaENSP00000369697.4
 
Nonsense mediated decay
Q4R1J8 -TSL:2
ENST00000560716.1APH1B-209731No protein-
 
Protein coding CDS not defined
--TSL:3
ENST00000559744.1APH1B-205456No protein-
 
Protein coding CDS not defined
--TSL:2
ENST00000559823.1APH1B-206376No protein-
 
Protein coding CDS not defined
--TSL:3
ENST00000558631.1APH1B-204515No protein-
 
Retained intron
--TSL:2
Statistics

Exons: 5, Coding exons: 5, Transcript length: 685 bps, Translation length: 216 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q8WW43

CCDS

This transcript is a member of the Human CCDS set: CCDS45276

Transcript Support Level (TSL)

TSL:1

Version

ENST00000380343.8

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.