Transcript: ENST00000366820.10 LEFTY2-201

Description

left-right determination factor 2 [Source:HGNC Symbol;Acc:HGNC:3122]

Gene Synonyms

EBAF, LEFTA, LEFTYA, TGFB4

Location

Chromosome 1: 225,936,603-225,941,220 reverse strand.

About this transcript

This transcript has 4 exons, is annotated with 29 domains and features, is associated with 2366 variant alleles and maps to 431 oligo probes.

Gene

This transcript is a product of gene ENSG00000143768.13 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000366820.10	LEFTY2-201	2019	366aa	ENSP00000355785.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS1549	O00292-1	NM_003240.5	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENST00000420304.6	LEFTY2-202	2085	332aa	ENSP00000388009.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS53479	O00292-2	-	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2,
ENST00000474493.1	LEFTY2-203	515	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	-	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3,

Summary

Statistics

Exons: 4, Coding exons: 4, Transcript length: 2,019 bps, Translation length: 366 residues

MANE

This MANE Select transcript contains ENSP00000355785 and matches to NM_003240.5 and NP_003231.2

Uniprot

This transcript corresponds to the following Uniprot identifiers: O00292

CCDS

This transcript is a member of the Human CCDS set: CCDS1549

Transcript Support Level (TSL)

TSL:1

Version

ENST00000366820.10

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript: ENST00000366820.10 LEFTY2-201

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Transcript: ENST00000366820.10 LEFTY2-201

Summary

About Us

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