Human (GRCh38.p14)
Description

DNA topoisomerase I [Source:HGNC Symbol;Acc:HGNC:11986]

Location
About this transcript

This transcript has 21 exons, is annotated with 47 domains and features, is associated with 39158 variant alleles and maps to 888 oligo probes.

Gene
Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000361337.3TOP1-2013734765aaENSP00000354522.2
 
Protein coding
CCDS13312P11387 NM_003286.4MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P1TSL:1
ENST00000680945.1TOP1-2022532296aaENSP00000504935.1
 
Protein coding
A0A7P0T852 -GENCODE basic
ENST00000681113.1TOP1-2043938204aaENSP00000505788.1
 
Nonsense mediated decay
A0A7P0T9R7 --
ENST00000681058.1TOP1-2038092No protein-
 
Retained intron
---
ENST00000681392.1TOP1-2054782No protein-
 
Retained intron
---
ENST00000681884.1TOP1-2064736No protein-
 
Retained intron
---
Statistics

Exons: 21, Coding exons: 21, Transcript length: 3,734 bps, Translation length: 765 residues

MANE

This MANE Select transcript contains ENSP00000354522 and matches to NM_003286.4 and NP_003277.1

Uniprot

This transcript corresponds to the following Uniprot identifiers: P11387

CCDS

This transcript is a member of the Human CCDS set: CCDS13312

Transcript Support Level (TSL)

TSL:1

Version

ENST00000361337.3

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.