Human (GRCh38.p14)
Description

mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840]

Gene Synonyms

MAPKK1, MEK1, PRKMK1

Location
About this transcript

This transcript has 11 exons, is annotated with 105 domains and features, is associated with 50965 variant alleles and maps to 557 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000307102.10MAP2K1-2012547393aaENSP00000302486.5
 
Protein coding
CCDS10216Q02750-1 NM_002755.4MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P1TSL:1
ENST00000689951.1MAP2K1-2112710410aaENSP00000509308.1
 
Protein coding
A0A8I5KRX5 -GENCODE basic
ENST00000685763.1MAP2K1-2062512344aaENSP00000509016.1
 
Protein coding
A0A8I5KXN4 -GENCODE basic
ENST00000691937.1MAP2K1-2142445317aaENSP00000508768.1
 
Protein coding
A0A8I5QJ96 -GENCODE basic
ENST00000691576.1MAP2K1-2132407350aaENSP00000510066.1
 
Protein coding
A0A8I5QJP8 -GENCODE basic
ENST00000685172.1MAP2K1-2052389417aaENSP00000509604.1
 
Protein coding
A0A8I5KYB4 -GENCODE basic
ENST00000692683.1MAP2K1-2162350371aaENSP00000508437.1
 
Protein coding
B4DFY5 -GENCODE basic
ENST00000686347.1MAP2K1-2072209284aaENSP00000509027.1
 
Protein coding
A0A8I5QJC1 -GENCODE basic
ENST00000693150.1MAP2K1-2172133345aaENSP00000510309.1
 
Protein coding
CCDS92029A0A8I5KYS7 -GENCODE basic
ENST00000566326.1MAP2K1-2031432217aaENSP00000456438.1
 
Protein coding
H3BRW9 -GENCODE basicTSL:5
ENST00000692487.1MAP2K1-2154868252aaENSP00000509534.1
 
Nonsense mediated decay
A0A8I5QJL9 --
ENST00000691077.1MAP2K1-2124428252aaENSP00000509843.1
 
Nonsense mediated decay
A0A8I5QJL9 --
ENST00000684779.1MAP2K1-2041887227aaENSP00000508681.1
 
Nonsense mediated decay
A0A8I5KVF6 --
ENST00000687191.1MAP2K1-2084354No protein-
 
Retained intron
---
ENST00000688689.1MAP2K1-2101855No protein-
 
Retained intron
---
ENST00000687481.1MAP2K1-2091526No protein-
 
Retained intron
---
ENST00000425818.2MAP2K1-2021338No protein-
 
Retained intron
--TSL:5
Statistics

Exons: 11, Coding exons: 11, Transcript length: 2,547 bps, Translation length: 393 residues

MANE

This MANE Select transcript contains ENSP00000302486 and matches to NM_002755.4 and NP_002746.1

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q02750

CCDS

This transcript is a member of the Human CCDS set: CCDS10216

Transcript Support Level (TSL)

TSL:1

Version

ENST00000307102.10

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.