Top 40 InterPro Domains in the Ensembl Database

No.

Interpro name	Number of genes	Number of Ensembl hits	No.	Interpro name	Number of genes	Number of Ensembl hits
1	IPR000719 Protein kinase, core	104	941	21	IPR007087 Zinc finger, C2H2-type	18	149
2	IPR001680 WD40 repeat	84	1279	22	IPR001395 Aldo/keto reductase	17	89
3	IPR000694 Proline-rich region	74	368	23	IPR000886 Endoplasmic reticulum targeting sequence	17	133
4	IPR000504 RNA recognition motif, RNP-1	58	379	24	IPR000330 SNF2-related	17	146
5	IPR001138 Fungal transcriptional regulatory protein, N-terminal	51	290	25	IPR001163 Like-Sm ribonucleoprotein, core	16	48
6	IPR001650 DNA/RNA helicase, C-terminal	38	204	26	IPR004762 Yeast amino acid permease	15	43
7	IPR001993 Mitochondrial substrate carrier	34	441	27	IPR000727 Target SNARE coiled-coil region	15	72
8	IPR000104 Antifreeze protein, type I	33	296	28	IPR002110 Ankyrin	15	160
9	IPR001806 Ras GTPase	32	428	29	IPR001623 Heat shock protein DnaJ, N-terminal	15	109
10	IPR000357 HEAT	29	195	30	IPR000608 Ubiquitin-conjugating enzyme, E2	15	62
11	IPR001841 Zinc finger, RING-type	27	111	31	IPR000073 Alpha/beta hydrolase fold-1	15	58
12	IPR003593 AAA+ ATPase, core	26	83	32	IPR011701 Major facilitator superfamily MFS-1	15	15
13	IPR000992 Stress-induced protein SRP1/TIP1	25	50	33	IPR000253 Forkhead-associated	15	120
14	IPR003663 Sugar transporter	24	227	34	IPR002198 Short-chain dehydrogenase/reductase SDR	14	144
15	IPR001142 Yeast membrane protein DUP	23	34	35	IPR001849 Pleckstrin-like	14	58
16	IPR001440 Tetratricopeptide TPR-1	22	383	36	IPR001005 SANT, DNA-binding	14	93
17	IPR000629 RNA helicase, ATP-dependent, DEAD-box type	21	116	37	IPR000182 GCN5-related N-acetyltransferase	13	26
18	IPR000533 Tropomyosin	21	109	38	IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2	13	63
19	IPR001584 Integrase, catalytic core	20	102	39	IPR003439 ABC transporter related	13	104
20	IPR004843 Metallophosphoesterase	19	124	40	IPR001412 Aminoacyl-tRNA synthetase, class I	13	112

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