Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle; catalyzes condensation of acetyl coenzyme A and oxaloacetate to form citrate; expression is controlled by Rtg1p and Rtg2p transcription factors; SCF-Ucc1 regulates level of Cit2p to maintain citrate homeostasis; oxaloacetate-dependent positive feedback loop inhibits Cit2p ubiquitination; CIT2 has a paralog, CIT1, that arose from the whole genome duplication [Source:SGD;Acc:S000000598]
Chromosome III: 120,946-122,328 reverse strand.
This transcript has 1 exon, is annotated with 16 domains and features, is associated with 21 variant alleles and maps to 28 oligo probes.
This transcript is a product of gene YCR005C Show transcript tableHide transcript table
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YCR005C_mRNA | CIT2 | 1383 | 460aa | YCR005C | Protein coding | P08679 | Ensembl Canonical, |