Saccharomyces cerevisiae (R64-1-1)
Description

Guanine nucleotide exchange factor (GEF) and ubiquitin receptor; involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF MUK1; required for localization of the CORVET complex to endosomes; similar to mammalian ras inhibitors; contains a Ub-interacting CUE domain [Source:SGD;Acc:S000004563]

Gene Synonyms

VPL31, VPT9

Location

Chromosome XIII: 78,335-79,690 reverse strand.

R64-1-1:BK006946.2

About this gene

This gene has 1 transcript (splice variant) and 201 orthologues.

Transcript IDNamebpProteinTranslation IDBiotypeUniProt MatchFlags
YML097C_mRNAVPS91356451aaYML097C
 
Protein coding
P54787 Ensembl Canonical