Description
Hexokinase isoenzyme 2; phosphorylates glucose in cytosol; predominant hexokinase during growth on glucose; represses expression of HXK1, GLK1, induces expression of its own gene; antiapoptotic; phosphorylation/dephosphorylation at Ser14 by kinase Snf1p, phosphatase Glc7p-Reg1p regulates nucleocytoplasmic shuttling of Hxk2p; functions downstream of Sit4p in control of cell cycle, mitochondrial function, oxidative stress resistance, chronological lifespan; has paralog HXK1 [Source:SGD;Acc:S000003222]
Gene Synonyms
HEX1, HKB, SCI2
Location
Chromosome VII: 23,935-25,395 forward strand.
R64-1-1:BK006941.2
About this gene
This gene has 1 transcript (splice variant), 1064 orthologues and 4 paralogues.
Transcripts
