Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: Sesn1 ENSRNOG00000000302

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Description

sestrin 1 [Source:RGD Symbol;Acc:1307517]

Gene Synonyms

LOC294518

Location

Primary_assembly 20: 45,294,871-45,387,697 forward strand.

mRatBN7.2:CM026993.1

About this gene

This gene has 3 transcripts (splice variants), 207 orthologues, 2 paralogues and is associated with 2 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000089611.2	Sesn1-202	3457	551aa	ENSRNOP00000073119.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A0G2K4P1	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS ALT1: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that is conserved in at least three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT1,
ENSRNOT00000065890.2	Sesn1-201	2850	462aa	ENSRNOP00000060435.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	D3ZJU4	-
ENSRNOT00000116987.1	Sesn1-203	2616	492aa	ENSRNOP00000090761.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6AEX8	APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,

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Summary

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