Gene: Map3k8 ENSRNOG00000016378

Description

mitogen-activated protein kinase kinase kinase 8 [Source:RGD Symbol;Acc:620969]

Gene Synonyms

D17TPL2, Tpl-2, Tpl2

Location

mRatBN7.2:CM026990.1

About this gene

This gene has 2 transcripts (splice variants), 198 orthologues, 36 paralogues and is associated with 24 phenotypes.

Transcripts

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSRNOT00000022190.4	Map3k8-201	2847	565aa	ENSRNOP00000022190.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	G3V840	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSRNOT00000119501.1	Map3k8-202	6242	515aa	ENSRNOP00000091878.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A8I6AGZ3	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,

Summary