Gene: Casp1 ENSMUSG00000025888

Description

caspase 1 [Source:MGI Symbol;Acc:MGI:96544]

Gene Synonyms

Caspase-1, ICE, Il1bc, interleukin 1 beta-converting enzyme

Location

Chromosome 9: 5,298,508-5,307,290 forward strand.

GRCm39:CM001002.3

About this gene

This gene has 5 transcripts (splice variants), 450 orthologues, 11 paralogues and is associated with 2 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000027015.7	Casp1-201	1531	402aa	ENSMUSP00000027015.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS22798	P29452	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000238505.2	Casp1-203	702	156aa	ENSMUSP00000158737.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A571BDI1	3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,
ENSMUST00000238730.2	Casp1-205	641	103aa	ENSMUSP00000158725.2	Nonsense mediated decay		A0A571BF22	5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,
ENSMUST00000238546.2	Casp1-204	2221	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-
ENSMUST00000238348.2	Casp1-202	2216	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-

Gene: Casp1 ENSMUSG00000025888

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Gene: Casp1 ENSMUSG00000025888

Summary

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