Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
- Genomic alignments
- Gene tree
- Gene gain/loss tree
- Orthologues
- Paralogues
- Strains
  - Gene tree
  - Orthologues
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Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
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Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: Lif ENSMUSG00000034394

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Description

leukemia inhibitory factor [Source:MGI Symbol;Acc:MGI:96787]

Location

Chromosome 11: 4,207,557-4,222,514 forward strand.

GRCm39:CM001004.3

About this gene

This gene has 3 transcripts (splice variants), 126 orthologues and is associated with 65 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000066283.12	Lif-202	4026	203aa	ENSMUSP00000067066.6	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS24383	P09056	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5,
ENSMUST00000040750.4	Lif-201	3798	158aa	ENSMUSP00000036853.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS24384	F8WH42	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000154927.2	Lif-203	390	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2,

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Summary

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