Description

apolipoprotein E [Source:MGI Symbol;Acc:MGI:88057]

Location
INSDC coordinates

chromosome:GRCm38:CM001000.2:19696109:19699166:1

About this gene

This gene has 10 transcripts (splice variants), 52 orthologues, is a member of 2 Ensembl protein families and is associated with 21 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
Apoe-001ENSMUST000001740641386311aaENSMUSP00000133302
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS20912G3UWN5 G3UWW2 G3UZT1
P08226 Q3TXU4 Q8C6E4
NM_009696
NP_033826
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
Apoe-006ENSMUST000001737391221311aaENSMUSP00000133371
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS20912G3UWN5 G3UWW2 G3UZT1
P08226 Q3TXU4 Q8C6E4
-TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
Apoe-009ENSMUST000000030661128311aaENSMUSP00000003066
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS20912G3UWN5 G3UWW2 G3UZT1
P08226 Q3TXU4 Q8C6E4
-TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
Apoe-010ENSMUST000001743551104311aaENSMUSP00000134160
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS20912G3UWN5 G3UWW2 G3UZT1
P08226 Q3TXU4 Q8C6E4
-TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
Apoe-004ENSMUST00000172983817232aaENSMUSP00000133359
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-G3UWN5 G3UWW2 G3UZT1
Q8C6E4
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Apoe-005ENSMUST00000174144816232aaENSMUSP00000134622
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-G3UWN5 G3UWW2 G3UZT1
Q8C6E4
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Apoe-002ENSMUST00000167646728221aaENSMUSP00000132032
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9Q327 G3UWW2 Q8C6E4
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Apoe-003ENSMUST0000017471051471aaENSMUSP00000134429
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-G3UWW2 Q8C6E4 -TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
Apoe-008ENSMUST0000017419147271aaENSMUSP00000133447
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-G3UWW2 Q8C6E4 -TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
Apoe-007ENSMUST00000172808456146aaENSMUSP00000134558
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-G3UZM8 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays