Description

major histocompatibility complex, class I, B [Source:HGNC Symbol;Acc:HGNC:4932]

Synonyms

AS

Gene

This transcript is a product of gene ENSG00000223532

This gene has 8 transcripts (splice variants) Show transcript tableHide transcript table

NameTranscript IDbpProteinBiotypeCCDSUniProtRefSeqFlags
HLA-B-001ENST000004258481605362 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A060VHG3 A2VBY1 A7WPJ0
B5B8Y7 B9VPM1 B9VWB1
C7C5G6 C7FDR9 C9E1F9
C9E1H5 C9E858 D2DKL7
D2DKP0 D2DKQ5 D2DKR8
D2DKS1 D2DKS3 D2DL39
D3U3S1 D3U3S2 D3U3S9
D4HP77 D4HP87 D4HPB1
D4HPK2 D4HPK9 D5FHY6
D5FZK2 D6CIN1 D7NNV2
D7NPQ0 D7NQX1 D7R0U5
E0X9I7 E1U682 E2DH86
E3Q1J1 E3SWH3 E7BYA0
E9LY24 F4YU54 F8RHF4
F8RHH0 G1ENH6 G1EPQ5
G3D6J9 G3D6K1 G9HW80
G9I2K5 I1W1M8 I3VZ14
I3VZ27 I4EC43 I7JHQ8
K0A005 K7P5K3 K9LD82
M1FUS4 M9P8Q9 M9PA20
O19564 O19568 O19691
P30460 P30462 P30475
P30479 Q155X3 Q29843
Q29923 Q2YHP4 Q4VYS9
Q5F311 Q5QR31 Q5QR33
Q5QR34 Q5QR36 Q5QR46
Q5QR47 Q5QR48 Q5QR57
Q5QR58 Q5QR59 Q5QR60
Q5QR62 Q5QR69 Q5QR73
Q5QR76 Q5QR83 Q5QR84
Q5QR85 Q5QR86 Q5QR87
Q5QR88 Q5SS57 Q6IUU8
Q6ZXT6 Q709M5 Q70HJ6
Q710M7 Q710M8 Q7YNX2
Q7YP17 Q861B6 Q861D4
Q861D6 Q861E5 Q8HWM2
Q8HWQ3 Q95365 Q9UE90
Q9UE96 R4ZGR5 V5NVK6
W0NT72
NM_005514
NP_005505
TSL:NA

TSL:NA:The transcript was not analyzed for one of the following reasons:

  • Pseudogene annotation, including transcribed pseudogenes
  • Human leukocyte antigen (HLA) transcript
  • Immunoglobin gene transcript
  • T-cell receptor transcript
  • Single-exon transcript (will be included in a future version)

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
HLA-B-006ENST000004167261154241 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-B9VWB1 Q29843 Q5F311
Q5QR31 Q5QR33 Q5QR34
Q5QR36 Q5QR46 Q5QR47
Q5QR48 Q5QR57 Q5QR58
Q5QR59 Q5QR60 Q6ZXT6
Q709M5 Q70HJ6 Q710M7
Q710M8 Q7YNX2 Q7YP17
Q861D4 Q861D6 Q861E5
Q8HWQ3
-CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:NA

TSL:NA:The transcript was not analyzed for one of the following reasons:

  • Pseudogene annotation, including transcribed pseudogenes
  • Human leukocyte antigen (HLA) transcript
  • Immunoglobin gene transcript
  • T-cell receptor transcript
  • Single-exon transcript (will be included in a future version)

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

HLA-B-003ENST00000445222863246 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A2VBY1 B5B8Y7 B9VPM1
C7C5G6 C7FDR9 C9E1F9
C9E1H5 C9E858 D2DKL7
D2DKP0 D2DKQ5 D2DKR8
D2DKS1 D2DKS3 D2DL39
D3U3S1 D3U3S2 D3U3S9
D4HP77 D4HP87 D4HPB1
D4HPK2 D4HPK9 D5FHY6
D5FZK2 D7NNV2 D7NPQ0
D7NQX1 D7R0U5 E0X9I7
E1U682 E2DH86 E3SWH3
E7BYA0 E9LY24 F4YU54
F8RHF4 F8RHH0 G1ENH6
G1EPQ5 G3D6J9 G3D6K1
G9HW80 G9I2K5 I1W1M8
I3VZ14 I3VZ27 K0A005
K7P5K3 K9LD82 M1FUS4
M9P8Q9 M9PA20 O19564
O19568 Q155X3 Q2YHP4
Q4VYS9 Q8HWM2 Q9UE90
Q9UE96 V5NVK6 W0NT72
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:NA

TSL:NA:The transcript was not analyzed for one of the following reasons:

  • Pseudogene annotation, including transcribed pseudogenes
  • Human leukocyte antigen (HLA) transcript
  • Immunoglobin gene transcript
  • T-cell receptor transcript
  • Single-exon transcript (will be included in a future version)

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

HLA-B-004ENST000004615831008224 aa
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-A2VBY1 B5B8Y7 B9VPM1
C7C5G6 C7FDR9 C9E1F9
C9E1H5 C9E858 D2DKL7
D2DKP0 D2DKQ5 D2DKR8
D2DKS1 D2DKS3 D2DL39
D3U3S1 D3U3S2 D3U3S9
D4HP77 D4HP87 D4HPB1
D4HPK2 D4HPK9 D5FHY6
D5FZK2 D7NNV2 D7NPQ0
D7NQX1 D7R0U5 E0X9I7
E1U682 E2DH86 E3SWH3
E7BYA0 E9LY24 F4YU54
F8RHF4 F8RHH0 G1ENH6
G1EPQ5 G3D6J9 G3D6K1
G9HW80 G9I2K5 I1W1M8
I3VZ14 I3VZ27 K0A005
K7P5K3 K9LD82 M1FUS4
M9P8Q9 M9PA20 O19564
O19568 Q155X3 Q2YHP4
Q4VYS9 Q5QR62 Q5QR69
Q5QR73 Q5QR76 Q5QR83
Q5QR84 Q5QR85 Q5QR86
Q5QR87 Q5QR88 Q8HWM2
Q9UE90 Q9UE96 V5NVK6
W0NT72
-TSL:NA

TSL:NA:The transcript was not analyzed for one of the following reasons:

  • Pseudogene annotation, including transcribed pseudogenes
  • Human leukocyte antigen (HLA) transcript
  • Immunoglobin gene transcript
  • T-cell receptor transcript
  • Single-exon transcript (will be included in a future version)

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

HLA-B-002ENST000004709151088No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:NA

TSL:NA:The transcript was not analyzed for one of the following reasons:

  • Pseudogene annotation, including transcribed pseudogenes
  • Human leukocyte antigen (HLA) transcript
  • Immunoglobin gene transcript
  • T-cell receptor transcript
  • Single-exon transcript (will be included in a future version)

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

HLA-B-007ENST00000473379917No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:NA

TSL:NA:The transcript was not analyzed for one of the following reasons:

  • Pseudogene annotation, including transcribed pseudogenes
  • Human leukocyte antigen (HLA) transcript
  • Immunoglobin gene transcript
  • T-cell receptor transcript
  • Single-exon transcript (will be included in a future version)

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

HLA-B-008ENST00000472294753No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:NA

TSL:NA:The transcript was not analyzed for one of the following reasons:

  • Pseudogene annotation, including transcribed pseudogenes
  • Human leukocyte antigen (HLA) transcript
  • Immunoglobin gene transcript
  • T-cell receptor transcript
  • Single-exon transcript (will be included in a future version)

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

HLA-B-005ENST00000490676586No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:NA

TSL:NA:The transcript was not analyzed for one of the following reasons:

  • Pseudogene annotation, including transcribed pseudogenes
  • Human leukocyte antigen (HLA) transcript
  • Immunoglobin gene transcript
  • T-cell receptor transcript
  • Single-exon transcript (will be included in a future version)

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 6 Coding exons: 4 Transcript length: 1,008 bps Translation length: 224 residues

Transcript Support Level

NA

Ensembl version

ENST00000461583.3

Type

Known nonsense mediated decay

Prediction Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:

Transcript-based displays