Description

transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) [Source:HGNC Symbol;Acc:HGNC:44]

Synonyms

ABCB3, D6S217E, PSF2, RING11

Location
Gene

This transcript is a product of gene ENSG00000204267

This gene has 5 transcripts (splice variants) Show transcript tableHide transcript table

NameTranscript IDbpProteinBiotypeCCDSUniProtRefSeqFlags
TAP2-002ENST000003748992497653 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS4755B6VNV2 Q03519 Q9UP03
NM_018833
NP_061313
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
TAP2-001ENST000003748975684686 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-B6VNV2 Q03519 Q5JNW1
NM_001290043
NP_001276972
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS CIAPPRIS candidate principal isoform
Glossary entry for APPRIS
APPRIS website
TAP2-201ENST000006201235676702 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-B6VNV2 Q5JNW1 NM_000544
NP_000535
TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS CI1APPRIS candidate principal isoform (longest coding sequence)
Glossary entry for APPRIS
APPRIS website
TAP2-003ENST00000485701274No protein
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

TAP2-004ENST00000464100849No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 12 Coding exons: 11 Transcript length: 5,684 bps Translation length: 686 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q03519

Transcript Support Level

1

Ensembl version

ENST00000374897.2

Type

Known protein coding

Prediction Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Stop codons

This transcript has a variant, rs241448, that causes a stop codon to be lost in at least 10% of HapMap or 1000 Genome population(s) CSHL-HAPMAP:HAPMAP-CHD, CSHL-HAPMAP:HapMap-HCB, CSHL-HAPMAP:HAPMAP-LWK, ESP6500:African_American, CSHL-HAPMAP:HapMap-JPT, CSHL-HAPMAP:HapMap-YRI, CSHL-HAPMAP:HAPMAP-GIH, ESP6500:European_American, CSHL-HAPMAP:HAPMAP-CHB, CSHL-HAPMAP:HAPMAP-MKK, CSHL-HAPMAP:HAPMAP-MEX, CSHL-HAPMAP:HAPMAP-TSI, CSHL-HAPMAP:HAPMAP-ASW, CSHL-HAPMAP:HapMap-CEU.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays