Description

transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) [Source:HGNC Symbol;Acc:HGNC:44]

Synonyms

ABCB3, D6S217E, PSF2, RING11

Location
About this transcript

This transcript has 12 exons, is annotated with 30 domains and features, is associated with 282 variations and maps to 38 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
TAP2-002ENST000003748992497653aaENSP00000364034
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS4755Q03519 Q9UP03 NM_018833
NP_061313
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
TAP2-001ENST000003748975684686aaENSP00000364032
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-Q03519 Q5JNW1 NM_001290043
NP_001276972
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT1

ALTERNATIVE1 - APPRIS candidate principal isoform that is conserved in at least three tested non-primate species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

TAP2-201ENST000006201235676702aaENSP00000481712
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A087WYD6 NM_000544
NP_000535
TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P5

PRINCIPAL5 - APPRIS candidate principal isoform (longest coding sequence).

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

TAP2-003ENST00000485701274No protein-
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:3

Transcript Support Level 3, when transcripts are supported by a single EST only.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

TAP2-004ENST00000464100849No protein-
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 12 Coding exons: 11 Transcript length: 2,497 bps Translation length: 653 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS4755

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q03519

Transcript Support Level (TSL)

TSL:1

Ensembl version

ENST00000374899.7

Type

Known protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays