Description

leucine-rich repeat kinase 2 [Source:HGNC Symbol;Acc:HGNC:18618]

Synonyms

DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2

Location
Gene

This transcript is a product of gene ENSG00000188906

This gene has 7 transcripts (splice variants) Show transcript tableHide transcript table

NameTranscript IDLengthProteinBiotypeCCDSUniProtRefSeqFlags
LRRK2-004ENST000002989109158 bp2527 aa (view)
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS31774Q5S007 NM_198578
NP_940980
GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
LRRK2-002ENST000003437424740 bp1271 aa (view)
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A2VED2 E9PC85 -GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
LRRK2-001ENST000004167961655 bp521 aa (view)
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-C9JBF0 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.
LRRK2-005ENST000004308046400 bp207 aa (view)
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
---CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.
LRRK2-007ENST00000481256561 bp No protein product
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---
LRRK2-003ENST000004791878306 bp No protein product
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---
LRRK2-006ENST00000474202556 bp No protein product
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---
Statistics

Exons: 51 Coding exons: 51 Transcript length: 9,158 bps Translation length: 2,527 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS31774

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q5S007

Ensembl version

ENST00000298910.8

Type

Known protein coding

Prediction Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays