Description

Wilms tumor 1 [Source:HGNC Symbol;Acc:HGNC:12796]

Synonyms

AWT1, GUD, WAGR, WIT-2

Location
Gene

This transcript is a product of gene ENSG00000184937

This gene has 9 transcripts (splice variants) Show transcript tableHide transcript table

NameTranscript IDbpProteinBiotypeCCDSUniProtRefSeqFlags
WT1-001ENST000003323513122517 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS7878A0FJ57 A0FJ58 A8MN20
E9PKS2 E9PPW3 H0Y3F0
J3KNN9 Q6LBI3
NM_024426
NP_077744
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS CI2APPRIS candidate principal isoform (longest CCDS) [01-09-2014]
Glossary entry for APPRIS
APPRIS website
WT1-004ENST000004528632768497 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS44561A0FJ57 A8MN20 E9PPW3
H0Y3F0
NM_000378
NP_000369
CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

APPRIS CIAPPRIS candidate principal isoform [01-09-2014]
Glossary entry for APPRIS
APPRIS website
WT1-002ENST000003790792466302 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS55751A0FJ57 A8MN20 E9PKS2
E9PPW3 P19544
NM_001198551
NP_001185480
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS CIAPPRIS candidate principal isoform [01-09-2014]
Glossary entry for APPRIS
APPRIS website
WT1-003ENST000005309982421288 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS55750A0FJ57 A0FJ58 A8MN20
E9PPW3 P19544 Q6LBI3
NM_001198552
NP_001185481
TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
WT1-009ENST000004480762114514 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS44562A0FJ57 A8MN20 E9PKS2
E9PPW3 H0Y3F0 H0Y7K5
NM_024424
NP_077742
TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS CIAPPRIS candidate principal isoform [01-09-2014]
Glossary entry for APPRIS
APPRIS website
WT1-007ENST0000052668571825 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PPW3 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

WT1-006ENST00000527775578131 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A8MN20 E9PKS2 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

WT1-008ENST00000527882551178 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0FJ58 A8MN20 E9PPW3
Q6LBI3
-CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

WT1-005ENST000003790773032317 aa
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-H0Y3F0 Q6PI38 -TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 10 Coding exons: 10 Transcript length: 3,122 bps Translation length: 517 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS7878

Transcript Support Level

1

Ensembl version

ENST00000332351.5

Type

Known protein coding

Prediction Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays