Description

protein tyrosine phosphatase, non-receptor type 11 [Source:HGNC Symbol;Acc:HGNC:9644]

Synonyms

BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2

About this transcript

This transcript has 16 exons, is annotated with 28 domains and features, is associated with 415 variations and maps to 63 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
PTPN11-001ENST000003516776101593aaENSP00000340944
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS9163Q06124 NM_002834
NP_002825
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

PTPN11-002ENST000003925971876460aaENSP00000376376
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS58280Q06124 NM_080601
NP_542168
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
PTPN11-004ENST00000530818486108aaENSP00000437013
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H0YF12 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:3

Transcript Support Level 3, when transcripts are supported by a single EST only.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PTPN11-003ENST00000531326573No protein-
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:4

Transcript Support Level 4, for transcripts supported by an EST flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 16 Coding exons: 15 Transcript length: 6,101 bps Translation length: 593 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS9163

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q06124

Transcript Support Level (TSL)

TSL:1

Ensembl version

ENST00000351677.5

Type

Known protein coding

Annotation Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays