Human (GRCh38.p14)
Description

DNA polymerase epsilon, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9177]

Gene Synonyms

POLE1

About this transcript

This transcript has 49 exons, is annotated with 26 domains and features, is associated with 44762 variant alleles and maps to 1247 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000320574.10POLE-20178232286aaENSP00000322570.5
 
Protein coding
CCDS9278Q07864 NM_006231.4MANE SelectEnsembl CanonicalGENCODE basicAPPRIS P1TSL:1
ENST00000535270.5POLE-20768002259aaENSP00000445753.1
 
Protein coding
F5H1D6 -GENCODE basicTSL:1
ENST00000672742.1POLE-2198673207aaENSP00000500279.1
 
Nonsense mediated decay
A0A5F9ZHD6 --
ENST00000699983.1POLE-2228340294aaENSP00000514737.1
 
Nonsense mediated decay
A0A8V8TQW1 -CDS 5' incomplete
ENST00000537064.5POLE-2088011310aaENSP00000442578.1
 
Nonsense mediated decay
F5H7E4 -TSL:1
ENST00000699982.1POLE-2217636294aaENSP00000514736.1
 
Nonsense mediated decay
A0A8V8TQW1 -CDS 5' incomplete
ENST00000699984.1POLE-2237561294aaENSP00000514738.1
 
Nonsense mediated decay
A0A8V8TQW1 -CDS 5' incomplete
ENST00000672002.1POLE-2185455308aaENSP00000500233.1
 
Nonsense mediated decay
A0A087WW42 -CDS 5' incomplete
ENST00000544870.6POLE-2165435308aaENSP00000479927.2
 
Nonsense mediated decay
A0A087WW42 -TSL:3CDS 5' incomplete
ENST00000434528.5POLE-2032406121aaENSP00000500921.1
 
Nonsense mediated decay
A0A5F9ZI42 -TSL:5CDS 5' incomplete
ENST00000539215.6POLE-210678147aaENSP00000514725.1
 
Nonsense mediated decay
A0A8V8TQH1 -TSL:5CDS 5' incomplete
ENST00000441786.3POLE-204556154aaENSP00000480727.1
 
Nonsense mediated decay
A0A087WX51 -TSL:5CDS 5' incomplete
ENST00000503265.5POLE-205556No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000538196.1POLE-209551No protein-
 
Protein coding CDS not defined
--TSL:4
ENST00000699981.1POLE-2205450No protein-
 
Retained intron
---
ENST00000416953.3POLE-2025004No protein-
 
Retained intron
--TSL:4
ENST00000541627.2POLE-2142105No protein-
 
Retained intron
--TSL:2
ENST00000545015.2POLE-2171812No protein-
 
Retained intron
--TSL:2
ENST00000699985.1POLE-2241012No protein-
 
Retained intron
---
ENST00000540987.1POLE-213587No protein-
 
Retained intron
--TSL:3
ENST00000544414.1POLE-215575No protein-
 
Retained intron
--TSL:2
ENST00000534922.6POLE-206567No protein-
 
Retained intron
--TSL:3
ENST00000539357.1POLE-211364No protein-
 
Retained intron
--TSL:3
ENST00000539618.1POLE-212299No protein-
 
Retained intron
--TSL:3
Statistics

Exons: 49, Coding exons: 49, Transcript length: 7,823 bps, Translation length: 2,286 residues

MANE

This MANE Select transcript contains ENSP00000322570 and matches to NM_006231.4 and NP_006222.2

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q07864

CCDS

This transcript is a member of the Human CCDS set: CCDS9278

Transcript Support Level (TSL)

TSL:1

Version

ENST00000320574.10

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.