Transcript: ENST00000309680.4 KRT2-201

Description

keratin 2 [Source:HGNC Symbol;Acc:HGNC:6439]

Gene Synonyms

KRT2A, KRTE

Location

Chromosome 12: 52,644,558-52,652,211 reverse strand.

About this transcript

This transcript has 9 exons, is annotated with 33 domains and features, is associated with 4206 variant alleles and maps to 425 oligo probes.

Gene

This transcript is a product of gene ENSG00000172867.4 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000309680.4	KRT2-201	2450	639aa	ENSP00000310861.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS8835	P35908	NM_000423.3	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENST00000547106.1	KRT2-202	621	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	-	TSL 4: A transcript where the best supporting EST is flagged as suspect The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:4,

Summary

Statistics

Exons: 9, Coding exons: 9, Transcript length: 2,450 bps, Translation length: 639 residues

MANE

This MANE Select transcript contains ENSP00000310861 and matches to NM_000423.3 and NP_000414.2

Uniprot

This transcript corresponds to the following Uniprot identifiers: P35908

CCDS

This transcript is a member of the Human CCDS set: CCDS8835

Transcript Support Level (TSL)

TSL:1

Version

ENST00000309680.4

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript: ENST00000309680.4 KRT2-201

Summary

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Transcript: ENST00000309680.4 KRT2-201

Summary

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