Description

chloride channel, voltage-sensitive 5 [Source:HGNC Symbol;Acc:HGNC:2023]

Synonyms

ClC-5, CLC5, DENTS, hCIC-K2, hClC-K2, NPHL1, NPHL2, XLRH, XRN

Location
About this transcript

This transcript has 12 exons, is annotated with 34 domains and features, is associated with 353 variations and maps to 8 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
CLCN5-001ENST0000037608810108816aaENSP00000365256
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS48115P51795 NM_001127898
NM_001127899
NP_001121370
NP_001121371
TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species
Glossary entry for APPRIS
APPRIS website
CLCN5-003ENST000003073673177746aaENSP00000304257
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS14328P51795 NM_001282163
NP_001269092
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI3APPRIS candidate principal isoform (earliest CCDS)
Glossary entry for APPRIS
APPRIS website
CLCN5-002ENST000003760913046816aaENSP00000365259
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS48115P51795 -TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species
Glossary entry for APPRIS
APPRIS website
CLCN5-004ENST000003761082660746aaENSP00000365276
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS14328P51795 NM_000084
NP_000075
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI3APPRIS candidate principal isoform (earliest CCDS)
Glossary entry for APPRIS
APPRIS website
CLCN5-005ENST0000048221844964aaENSP00000476732
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS69763V9GYG7 NM_001272102
NP_001259031
TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
Statistics

Exons: 12 Coding exons: 11 Transcript length: 2,660 bps Translation length: 746 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS14328

Uniprot

This transcript corresponds to the following Uniprot identifiers: P51795

Transcript Support Level (TSL)

TSL:1

Ensembl version

ENST00000376108.6

Type

Known protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays