Description

mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840]

Synonyms

MAPKK1, MEK1, PRKMK1

Location
About this transcript

This transcript has 11 exons, is annotated with 12 domains and features, is associated with 154 variations and maps to 34 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
MAP2K1-001ENST000003071023410393aaENSP00000302486
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS10216A4QPA9 Q02750 NM_002755
NP_002746
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

MAP2K1-003ENST000005663261432217aaENSP00000456438
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H3BRW9 -TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
MAP2K1-002ENST000004258181338No protein-
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 11 Coding exons: 11 Transcript length: 3,410 bps Translation length: 393 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS10216

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q02750

Transcript Support Level (TSL)

TSL:1

Ensembl version

ENST00000307102.8

Type

Known protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays