Description

PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282]

Synonyms

CT84, FLJ14385, Nori-3, SPK, TOPK

Location
About this transcript

This transcript has 6 exons, is associated with 22 variations and maps to 20 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
PBK-001ENST000003019052118322aaENSP00000301905
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS6063Q96KB5 V9HWH0 NM_018492
NP_060962
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

PBK-002ENST000005229441499333aaENSP00000428489
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS64858Q96KB5 NM_001278945
NP_001265874
TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
PBK-005ENST00000521226748151aaENSP00000427892
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E5RFX4 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

Transcript Support Level 3, when transcripts are supported by a single EST only.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PBK-006ENST0000052426681963aaENSP00000428438
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-E5RIE1 -TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 6 Coding exons: 3 Transcript length: 819 bps Translation length: 63 residues

Transcript Support Level (TSL)

TSL:5

Ensembl version

ENST00000524266.1

Type

Known nonsense mediated decay

Annotation Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:

Transcript-based displays