Description

inducible T-cell co-stimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087]

Synonyms

B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653

Location
About this transcript

This transcript has 6 exons, is annotated with 8 domains and features, is associated with 56 variations and maps to 18 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
ICOSLG-001ENST000004077807080302aaENSP00000384432
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS42952A0N0L8 O75144 NM_001283052
NM_015259
NP_001269981
NP_056074
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI3APPRIS candidate principal isoform (earliest CCDS)
Glossary entry for APPRIS
APPRIS website
ICOSLG-002ENST000004003772907185aaENSP00000383228
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS63377O75144 NM_001283051
NP_001269980
TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
ICOSLG-003ENST000003443301009309aaENSP00000339477
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS63379O75144 NM_001283050
NP_001269979
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species
Glossary entry for APPRIS
APPRIS website
ICOSLG-004ENST000004003794246473aaENSP00000383230
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-K4DIA0 -TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species
Glossary entry for APPRIS
APPRIS website
Statistics

Exons: 6 Coding exons: 6 Transcript length: 2,907 bps Translation length: 185 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS63377

Uniprot

This transcript corresponds to the following Uniprot identifiers: O75144

Transcript Support Level (TSL)

TSL:2

Ensembl version

ENST00000400377.3

Type

Novel protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays