Human (GRCh38.p14)
Description

inducible T cell costimulator ligand [Source:HGNC Symbol;Acc:HGNC:17087]

Gene Synonyms

B7-H2, B7H, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653

Location
About this transcript

This transcript has 6 exons, is annotated with 10 domains and features, is associated with 3833 variant alleles and maps to 448 oligo probes.

Transcript IDNamebpProteinTranslation IDBiotypeCCDSUniProt MatchRefSeq MatchFlags
ENST00000407780.8ICOSLG-2047078302aaENSP00000384432.3
 
Protein coding
CCDS42952O75144-1 NM_015259.6MANE SelectEnsembl CanonicalGENCODE basicAPPRIS ALT2TSL:1
ENST00000400379.8ICOSLG-2034317473aaENSP00000383230.3
 
Protein coding
K4DIA0 -GENCODE basicAPPRIS P4TSL:1
ENST00000643466.2ICOSLG-2053887361aaENSP00000494882.2
 
Protein coding
A0A2R8Y5W7 -GENCODE basicAPPRIS ALT2
ENST00000700361.1ICOSLG-2173688240aaENSP00000514963.1
 
Protein coding
A0A8V8TQ73 -GENCODE basicAPPRIS ALT2
ENST00000400377.4ICOSLG-2023387185aaENSP00000383228.3
 
Protein coding
CCDS63377O75144-3 -GENCODE basicTSL:2
ENST00000700352.1ICOSLG-2083103261aaENSP00000514956.1
 
Protein coding
A0A8V8TQ42 -GENCODE basic
ENST00000700355.1ICOSLG-2113089304aaENSP00000514957.1
 
Protein coding
CCDS93104A0A8V8TQV9 -GENCODE basicAPPRIS ALT2
ENST00000700358.1ICOSLG-2142558217aaENSP00000514960.1
 
Protein coding
CCDS93102B7Z1W8 -GENCODE basic
ENST00000344330.9ICOSLG-2011470309aaENSP00000339477.4
 
Protein coding
CCDS63379O75144-2 -GENCODE basicAPPRIS ALT2TSL:1
ENST00000700360.1ICOSLG-216865214aaENSP00000514962.1
 
Protein coding
A0A8V8TQW2 -CDS 3' incomplete
ENST00000700350.1ICOSLG-206351335aaENSP00000514955.1
 
Nonsense mediated decay
A0A8V8TR62 --
ENST00000700356.1ICOSLG-212293835aaENSP00000514958.1
 
Nonsense mediated decay
A0A8V8TR62 --
ENST00000700357.1ICOSLG-213269735aaENSP00000514959.1
 
Nonsense mediated decay
A0A8V8TR62 --
ENST00000700359.1ICOSLG-21599877aaENSP00000514961.1
 
Nonsense mediated decay
A0A096LPE5 --
ENST00000700354.1ICOSLG-2105416No protein-
 
Retained intron
---
ENST00000700351.1ICOSLG-2075413No protein-
 
Retained intron
---
ENST00000700353.1ICOSLG-2093614No protein-
 
Retained intron
---
Statistics

Exons: 6, Coding exons: 6, Transcript length: 3,387 bps, Translation length: 185 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: O75144

CCDS

This transcript is a member of the Human CCDS set: CCDS63377

Transcript Support Level (TSL)

TSL:2

Version

ENST00000400377.4

Type

Protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Havana manual annotation have the same sequence, for every base pair. See article.

Annotation Attributes

RNA-Seq supported only [Definitions]

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.