Description

ADAM metallopeptidase domain 17 [Source:HGNC Symbol;Acc:HGNC:195]

Synonyms

CD156B, cSVP, TACE

Location
About this transcript

This transcript has 19 exons, is annotated with 13 domains and features, is associated with 170 variations and maps to 22 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
ADAM17-001ENST000003108234349824aaENSP00000309968
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS1665B2RNB2 P78536 NM_003183
NP_003174
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
ADAM17-201ENST000006189231881258aaENSP00000480552
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A6H8L4 -TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
ADAM17-003ENST000004971341873285aaENSP00000418728
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E7EUI5 -TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
ADAM17-002ENST000004780591073No protein-
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 19 Coding exons: 19 Transcript length: 4,349 bps Translation length: 824 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS1665

Uniprot

This transcript corresponds to the following Uniprot identifiers: P78536

Transcript Support Level (TSL)

TSL:1

Ensembl version

ENST00000310823.6

Type

Known protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays