Description

apolipoprotein E [Source:HGNC Symbol;Acc:HGNC:613]

Synonyms

AD2

Location
Gene

This transcript is a product of gene ENSG00000130203

This gene has 5 transcripts (splice variants) Show transcript tableHide transcript table

NameTranscript IDbpProteinBiotypeCCDSUniProtRefSeqFlags
APOE-001ENST000002524861208317 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS12647E7ERP7 E9PEV4 J9ZVQ3
P02649 Q6LA97 Q6LBZ1
NM_000041
NP_000032
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
APOE-005ENST00000425718923219 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E7ERP7 E9PEV4 Q6LA97
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

APOE-004ENST00000434152864269 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E7ERP7 E9PEV4 H0Y7L5
Q6LA97 Q6LBZ1
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

APOE-002ENST00000446996737216 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PEV4 Q6LA97 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

APOE-003ENST00000485628771No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 4 Coding exons: 3 Transcript length: 1,208 bps Translation length: 317 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS12647

Uniprot

This transcript corresponds to the following Uniprot identifiers: P02649

Transcript Support Level

1

Ensembl version

ENST00000252486.6

Type

Known protein coding

Prediction Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays