Description

apolipoprotein E [Source:HGNC Symbol;Acc:HGNC:613]

Synonyms

AD2

Location
About this transcript

This transcript has 4 exons, is annotated with 8 domains and features, is associated with 138 variations and maps to 14 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
APOE-001ENST000002524861208317aaENSP00000252486
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS12647P02649 NM_000041
NM_001302689
NM_001302691
NP_000032
NP_001289617
NP_001289618
NP_001289619
NP_001289620
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
APOE-005ENST00000425718923219aaENSP00000410423
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E7ERP7 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

APOE-004ENST00000434152864269aaENSP00000413653
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H0Y7L5 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

APOE-002ENST00000446996737216aaENSP00000413135
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PEV4 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

APOE-003ENST00000485628771No protein-
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 4 Coding exons: 3 Transcript length: 1,208 bps Translation length: 317 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS12647

Uniprot

This transcript corresponds to the following Uniprot identifiers: P02649

Transcript Support Level (TSL)

TSL:1

Ensembl version

ENST00000252486.7

Type

Known protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays