Description

fms-related tyrosine kinase 3 [Source:HGNC Symbol;Acc:HGNC:3765]

Synonyms

CD135, FLK2, STK1

Location
About this transcript

This transcript has 24 exons, is annotated with 17 domains and features, is associated with 589 variations and maps to 10 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
FLT3-001ENST000002414533842993aaENSP00000241453
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS31953P36888 NM_004119
NP_004110
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
FLT3-002ENST000003809873634739aaENSP00000370374
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-E7ER61 -TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

FLT3-003ENST00000469894474No protein-
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 24 Coding exons: 24 Transcript length: 3,842 bps Translation length: 993 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS31953

Uniprot

This transcript corresponds to the following Uniprot identifiers: P36888

Transcript Support Level (TSL)

TSL:1

Ensembl version

ENST00000241453.10

Type

Known protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays