Description

cubilin (intrinsic factor-cobalamin receptor) [Source:HGNC Symbol;Acc:HGNC:2548]

Synonyms

gp280, IFCR, MGA1

Location
About this transcript

This transcript has 67 exons, is annotated with 145 domains and features, is associated with 1407 variations and maps to 9 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
CUBN-001ENST00000377833119493623aaENSP00000367064
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS7113O60494 NM_001081
NP_001072
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
CUBN-004ENST00000433666958105aaENSP00000415970
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H7C480 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CUBN-003ENST00000377823705170aaENSP00000367054
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-B0YIZ6 -TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
CUBN-002ENST0000043825459988aaENSP00000391830
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-Q5JQ33 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 67 Coding exons: 67 Transcript length: 11,949 bps Translation length: 3,623 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS7113

Uniprot

This transcript corresponds to the following Uniprot identifiers: O60494

Transcript Support Level (TSL)

TSL:1

Ensembl version

ENST00000377833.7

Type

Known protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
Annotation Attributes

low sequence quality [Definitions]

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays