Description

transforming growth factor, beta receptor 1 [Source:HGNC Symbol;Acc:HGNC:11772]

Synonyms

ACVRLK4, ALK-5, ESS1, MSSE

Location
Gene

This transcript is a product of gene ENSG00000106799

This gene has 10 transcripts (splice variants) Show transcript tableHide transcript table

NameTranscript IDbpProteinBiotypeCCDSUniProtRefSeqFlags
TGFBR1-001ENST000003749946516503 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS6738B4DY26 F8VVC4 P36897
Q5T7S2 TGFBR1-001
NM_004612
NP_004603
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform [01-09-2014]
Glossary entry for APPRIS
APPRIS website
TGFBR1-003ENST000003749905720426 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS47998F8VXZ5 P36897 TGFBR1-003
NM_001130916
NP_001124388
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
TGFBR1-004ENST000005525165933507 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F8VRH6 F8W0K6 P36897
TGFBR1-004
-TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
TGFBR1-007ENST000005502531538434 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-B4DY26 F8VVC4 TGFBR1-007
-TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
TGFBR1-010ENST00000549021680114 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F8VXZ5 TGFBR1-010 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

TGFBR1-011ENST00000548365582114 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F8VRH6 TGFBR1-011 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

TGFBR1-012ENST00000546584565188 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F8VVC4 H0YHS4 TGFBR1-012
-CDS 5' and 3' incomplete5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

TGFBR1-008ENST00000547314533118 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F8VVC4 TGFBR1-008 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

TGFBR1-009ENST00000552573526126 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F8VRH6 F8W0K6 TGFBR1-009
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

TGFBR1-005ENST000005497661678383 aa
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-F8VRH6 F8W0K6 F8W1R9
TGFBR1-005
-TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 8 Coding exons: 8 Transcript length: 5,720 bps Translation length: 426 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS47998

Uniprot

This transcript corresponds to the following Uniprot identifiers: P36897

Transcript Support Level

1

Ensembl version

ENST00000374990.4

Type

Known protein coding

Prediction Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays