Description

fatty acid 2-hydroxylase [Source:HGNC Symbol;Acc:HGNC:21197]

Synonyms

FAAH, FAXDC1, FLJ25287, SPG35

Location
About this transcript

This transcript has 7 exons, is annotated with 14 domains and features, is associated with 126 variations and maps to 27 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
FA2H-001ENST000002193682424372aaENSP00000219368
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS10911Q7L5A8 NM_024306
NP_077282
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

FA2H-004ENST00000569949578192aaENSP00000464576
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-J3QS89 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

Transcript Support Level 4, for transcripts supported by an EST flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

FA2H-005ENST0000061893329218aaENSP00000479548
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A087WVM8 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:NA

Transcript Support Level Not Analysed. Pseudogenes, single exon transcripts, HLA, T-cell receptor and Ig transcripts are not analysed and therefore not given any of the TSL categories.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

FA2H-002ENST000005676831537156aaENSP00000455126
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-H3BP32 -TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

FA2H-003ENST000005621452075No protein-
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 7 Coding exons: 7 Transcript length: 2,424 bps Translation length: 372 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS10911

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q7L5A8

Transcript Support Level (TSL)

TSL:1

Ensembl version

ENST00000219368.6

Type

Known protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays