Transcript: ENST00000455558.2 GRK3-202

Description

G protein-coupled receptor kinase 3 [Source:HGNC Symbol;Acc:HGNC:290]

Gene Synonyms

ADRBK2, BARK2

Location

Chromosome 22: 25,565,107-25,684,568 forward strand.

About this transcript

This transcript has 9 exons, is annotated with 1 domain and feature, is associated with 46870 variant alleles and maps to 189 oligo probes.

Gene

This transcript is a product of gene ENSG00000100077.16 Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	RefSeq Match	Flags
ENST00000324198.11	GRK3-201	9277	688aa	ENSP00000317578.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS13832	A0A024R1D8 P35626	NM_005160.4	The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select, A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENST00000455558.2	GRK3-202	657	45aa	ENSP00000393688.2	Nonsense mediated decay		H7C099	-	TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5, 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete,

Summary

Statistics

Exons: 9, Coding exons: 3, Transcript length: 657 bps, Translation length: 45 residues

Transcript Support Level (TSL)

TSL:5

Incomplete CDS

5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete

Version

ENST00000455558.2

Type

Nonsense mediated decay

Annotation Method

Manual annotation (determined on a case-by-case basis) from the Havana project.

Annotation Attributes

not organism-supported [Definitions]

Transcript: ENST00000455558.2 GRK3-202

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Transcript: ENST00000455558.2 GRK3-202

Summary

About Us

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