Description

5'-aminolevulinate synthase 1 [Source:HGNC Symbol;Acc:HGNC:396]

Synonyms

ALAS, ALAS3

Location
About this transcript

This transcript has 11 exons, is annotated with 8 domains and features, is associated with 188 variations and maps to 35 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
ALAS1-001ENST000003949652430640aaENSP00000378416
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS2847P13196 Q5JAM2 NM_000688
NM_001304444
NP_000679
NP_001291373
TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

ALAS1-004ENST000004849522356640aaENSP00000418779
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS2847P13196 Q5JAM2 -TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

ALAS1-003ENST000003102712212640aaENSP00000309259
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS2847P13196 Q5JAM2 NM_001304443
NM_199166
NP_001291372
NP_954635
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

ALAS1-002ENST000004692242125640aaENSP00000417719
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS2847P13196 Q5JAM2 -TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

ALAS1-007ENST00000493402758237aaENSP00000417352
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H7C4H7 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:3

Transcript Support Level 3, when transcripts are supported by a single EST only.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

ALAS1-006ENST00000459884350117aaENSP00000419423
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H7C5B0 -CDS 5' and 3' incomplete5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.TSL:2

Transcript Support Level 2, when transcripts are supported by multiple ESTs or by an mRNA flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 11 Coding exons: 10 Transcript length: 2,125 bps Translation length: 640 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS2847

Uniprot

This transcript corresponds to the following Uniprot identifiers: P13196

Transcript Support Level (TSL)

TSL:1

Ensembl version

ENST00000469224.4

Type

Known protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays