Description

mitogen-activated protein kinase kinase 1 [Source:HGNC Symbol;Acc:HGNC:6840]

Synonyms

MAPKK1, MEK1, PRKMK1

Location
About this transcript

This transcript has 7 exons, is annotated with 6 domains and features, is associated with 60 variations and maps to 25 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
MAP2K1-001ENST000003071023410393aaENSP00000302486
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS10216A4QPA9 Q02750 NM_002755
NP_002746
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

MAP2K1-003ENST000005663261432217aaENSP00000456438
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-H3BRW9 -TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
MAP2K1-002ENST000004258181338No protein-
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Protein domains for ENSP00000456438.1

Transcript-based displays