Description

cathepsin B [Source:HGNC Symbol;Acc:HGNC:2527]

Location
Gene

This transcript is a product of gene ENSG00000164733

This gene has 33 transcripts (splice variants) Show transcript tableHide transcript table

NameTranscript IDbpProteinBiotypeCCDSUniProtRefSeqFlags
CTSB-001ENST000003530473875339 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS5986A0A024R374 E9PHZ5 E9PID0
E9PIS1 E9PJ67 E9PKQ7
E9PKX0 E9PL32 E9PLY3
E9PNL5 E9PQM1 E9PR00
E9PR54 E9PS78 E9PSG5
P07858 Q8TAC7 R4GMQ5
NM_001908
NP_001899
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
CTSB-007ENST000003451252028339 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS5986A0A024R374 E9PHZ5 E9PID0
E9PIS1 E9PJ67 E9PKQ7
E9PKX0 E9PL32 E9PLY3
E9PNL5 E9PQM1 E9PR00
E9PR54 E9PS78 E9PSG5
P07858 Q8TAC7 R4GMQ5
NM_147781
NP_680091
TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
CTSB-006ENST000004535272011339 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS5986A0A024R374 E9PHZ5 E9PID0
E9PIS1 E9PJ67 E9PKQ7
E9PKX0 E9PL32 E9PLY3
E9PNL5 E9PQM1 E9PR00
E9PR54 E9PS78 E9PSG5
P07858 Q8TAC7 R4GMQ5
NM_147783
NP_680093
TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
CTSB-002ENST000005334552009339 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS5986A0A024R374 E9PHZ5 E9PID0
E9PIS1 E9PJ67 E9PKQ7
E9PKX0 E9PL32 E9PLY3
E9PNL5 E9PQM1 E9PR00
E9PR54 E9PS78 E9PSG5
P07858 Q8TAC7 R4GMQ5
NM_147780
NM_147782
NP_680090
NP_680092
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
CTSB-005ENST000005345101989339 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS5986A0A024R374 E9PHZ5 E9PID0
E9PIS1 E9PJ67 E9PKQ7
E9PKX0 E9PL32 E9PLY3
E9PNL5 E9PQM1 E9PR00
E9PR54 E9PS78 E9PSG5
P07858 Q8TAC7 R4GMQ5
-TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
CTSB-004ENST000005310891436339 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS5986A0A024R374 E9PHZ5 E9PID0
E9PIS1 E9PJ67 E9PKQ7
E9PKX0 E9PL32 E9PLY3
E9PNL5 E9PQM1 E9PR00
E9PR54 E9PS78 E9PSG5
P07858 Q8TAC7 R4GMQ5
-TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
CTSB-003ENST000005306401389339 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS5986A0A024R374 E9PHZ5 E9PID0
E9PIS1 E9PJ67 E9PKQ7
E9PKX0 E9PL32 E9PLY3
E9PNL5 E9PQM1 E9PR00
E9PR54 E9PS78 E9PSG5
P07858 Q8TAC7 R4GMQ5
-TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
CTSB-017ENST00000533572975170 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PHZ5 E9PID0 E9PIS1
E9PJ67 E9PKQ7 E9PKX0
E9PL32 E9PLY3 E9PNL5
E9PR00 E9PR54 E9PS78
E9PSG5
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-023ENST0000053438276470 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PID0 E9PIS1 E9PKX0
E9PL32 E9PR00
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-015ENST00000534636633175 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PHZ5 E9PID0 E9PIS1
E9PJ67 E9PKQ7 E9PKX0
E9PL32 E9PLY3 E9PNL5
E9PQM1 E9PR00 E9PR54
E9PS78 E9PSG5
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-021ENST00000527243580143 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PID0 E9PIS1 E9PJ67
E9PKQ7 E9PKX0 E9PL32
E9PNL5 E9PR00 E9PR54
E9PS78
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-016ENST0000052450057398 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PID0 E9PIS1 E9PKX0
E9PL32 E9PR00 E9PR54
E9PS78
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-030ENST0000053265657370 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PID0 E9PIS1 E9PKX0
E9PL32 E9PR00
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-024ENST0000053239257021 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PR00 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-019ENST00000530296561165 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PHZ5 E9PID0 E9PIS1
E9PJ67 E9PKQ7 E9PKX0
E9PL32 E9PLY3 E9PNL5
E9PR00 E9PR54 E9PS78
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-020ENST00000526195560149 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PHZ5 E9PID0 E9PIS1
E9PJ67 E9PKQ7 E9PKX0
E9PL32 E9PNL5 E9PR00
E9PR54 E9PS78
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-027ENST00000526645559136 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PID0 E9PIS1 E9PJ67
E9PKQ7 E9PKX0 E9PL32
E9PR00 E9PR54 E9PS78
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-013ENST0000053150255792 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PID0 E9PIS1 E9PKX0
E9PL32 E9PR00 E9PS78
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-032ENST0000052896555655 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PID0 E9PIS1 E9PR00
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-014ENST0000052721554568 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PID0 E9PIS1 E9PL32
E9PR00
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-033ENST00000505496540101 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PID0 E9PIS1 E9PJ67
E9PKX0 E9PL32 E9PR00
E9PR54 E9PS78
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-018ENST00000534149524143 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PID0 E9PIS1 E9PJ67
E9PKQ7 E9PKX0 E9PL32
E9PNL5 E9PR00 E9PR54
E9PS78
-CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-025ENST0000052465436832 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9PID0 E9PR00 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-011ENST000005315511855110 aa
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-E9PCB3 E9PID0 E9PIS1
E9PJ67 E9PKX0 E9PL32
E9PR00 E9PR54 E9PS78
-TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-042ENST0000052648166076 aa
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-R4GMQ5 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-026ENST00000525076550No protein
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-038ENST00000530290498No protein
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-039ENST00000530624430No protein
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-037ENST00000533110399No protein
 
Processed transcriptTranscripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.
---TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-041ENST000004206922230No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-036ENST00000532409839No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-035ENST00000532370693No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

CTSB-034ENST00000525315586No protein
 
Retained intronAlternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.
---TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Protein domains for ENSP00000409917.2

Transcript-based displays