Description

methylenetetrahydrofolate reductase [Source:HGNC Symbol;Acc:HGNC:7436]

Location

Chromosome 1: 11,785,723-11,806,920 reverse strand.

GRCh38:CM000663.2

About this gene

This gene has 19 transcripts (splice variants), 82 orthologues, is a member of 1 Ensembl protein family and is associated with 16 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
MTHFR-205ENST00000376592.68378656aaENSP00000365777
 
Protein coding
CCDS137P42898 -TSL:1GENCODE basicAPPRIS P3
MTHFR-203ENST00000376585.68094697aaENSP00000365770
 
Protein coding
CCDS81262P42898 NP_001317287
TSL:5GENCODE basicAPPRIS ALT1
MTHFR-204ENST00000376590.87094656aaENSP00000365775
 
Protein coding
CCDS137P42898 NM_005957
NP_005948
TSL:1GENCODE basicAPPRIS P3
MTHFR-202ENST00000376583.77044697aaENSP00000365767
 
Protein coding
CCDS81262P42898 NP_001317287
TSL:5GENCODE basicAPPRIS ALT1
MTHFR-210ENST00000641407.12387642aaENSP00000493098
 
Protein coding
---GENCODE basic
MTHFR-217ENST00000641820.11569411aaENSP00000492937
 
Protein coding
-L7P8G6 -GENCODE basic
MTHFR-207ENST00000418034.11034143aaENSP00000405082
 
Protein coding
-Q5SNW5 -CDS 3' incompleteTSL:3
MTHFR-201ENST00000376486.3875229aaENSP00000365669
 
Protein coding
-A0A1B0GXD9 -CDS 3' incompleteTSL:1
MTHFR-208ENST00000423400.6479155aaENSP00000398908
 
Protein coding
-Q5SNW7 -CDS 3' incompleteTSL:1
MTHFR-206ENST00000413656.539829aaENSP00000408307
 
Protein coding
-A0A1B0GXD9 -CDS 3' incompleteTSL:1
MTHFR-214ENST00000641747.1322782aaENSP00000493116
 
Nonsense mediated decay
---
MTHFR-212ENST00000641446.12820549aaENSP00000493262
 
Nonsense mediated decay
---
MTHFR-209ENST00000431243.61116No protein-
 
Processed transcript
---TSL:1
MTHFR-213ENST00000641721.1891No protein-
 
Processed transcript
---
MTHFR-219ENST00000642002.1549No protein-
 
Processed transcript
---
MTHFR-216ENST00000641805.12945No protein-
 
Retained intron
---
MTHFR-215ENST00000641759.12454No protein-
 
Retained intron
---
MTHFR-218ENST00000641909.12254No protein-
 
Retained intron
---
MTHFR-211ENST00000641437.11911No protein-
 
Retained intron
---

Gene-based displays