Description

erb-b2 receptor tyrosine kinase 2 [Source:HGNC Symbol;Acc:HGNC:3430]

Synonyms

CD340, NEU, HER-2, HER2, NGL

Location

Chromosome 17: 39,687,914-39,730,426 forward strand.

GRCh38:CM000679.2

About this gene

This gene has 22 transcripts (splice variants), 83 orthologues, 9 paralogues, is a member of 1 Ensembl protein family and is associated with 54 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
ERBB2-219ENST00000584601.547921225aaENSP00000462438
 
Protein coding
CCDS45667P04626 NM_001005862
NM_001289936
NP_001005862
NP_001276865
TSL:2GENCODE basic
ERBB2-202ENST00000406381.645641225aaENSP00000385185
 
Protein coding
CCDS45667P04626 -TSL:5GENCODE basic
ERBB2-201ENST00000269571.945451255aaENSP00000269571
 
Protein coding
CCDS32642P04626 X5DNK3 NM_004448
NP_004439
TSL:1GENCODE basicAPPRIS P1
ERBB2-204ENST00000541774.543411240aaENSP00000446466
 
Protein coding
CCDS74052P04626 -TSL:5GENCODE basic
ERBB2-218ENST00000584450.537301055aaENSP00000463714
 
Protein coding
CCDS77016J3QLU9 NM_001289937
NP_001276866
TSL:1GENCODE basic
ERBB2-205ENST00000578199.52526603aaENSP00000462808
 
Protein coding
CCDS77017F5H1T4 NM_001289938
NP_001276867
TSL:1GENCODE basic
ERBB2-203ENST00000445658.63238979aaENSP00000404047
 
Protein coding
-B4DTR1 -TSL:2GENCODE basic
ERBB2-210ENST00000580074.1754251aaENSP00000463002
 
Protein coding
-J3KTI5 -CDS 5' and 3' incompleteTSL:3
ERBB2-209ENST00000578709.5559102aaENSP00000463719
 
Protein coding
-J3QLV2 -CDS 3' incompleteTSL:4
ERBB2-213ENST00000582818.5529177aaENSP00000464252
 
Protein coding
-J3QRJ7 -CDS 5' and 3' incompleteTSL:3
ERBB2-207ENST00000578502.1497166aaENSP00000464420
 
Protein coding
-J3QRX1 -CDS 5' and 3' incompleteTSL:5
ERBB2-206ENST00000578373.5452390aaENSP00000463427
 
Nonsense mediated decay
-J3QL83 NR_110535
TSL:1
ERBB2-211ENST00000582648.5101396aaENSP00000462024
 
Nonsense mediated decay
-J3KRI9 -TSL:5
ERBB2-217ENST00000584099.1583No protein-
 
Processed transcript
---TSL:4
ERBB2-221ENST00000584888.1500No protein-
 
Processed transcript
---TSL:3
ERBB2-214ENST00000583038.54930No protein-
 
Retained intron
---TSL:2
ERBB2-212ENST00000582788.52004No protein-
 
Retained intron
---TSL:5
ERBB2-222ENST00000584908.51316No protein-
 
Retained intron
---TSL:1
ERBB2-208ENST00000578630.1874No protein-
 
Retained intron
---TSL:2
ERBB2-216ENST00000584014.5849No protein-
 
Retained intron
---TSL:1
ERBB2-220ENST00000584684.1649No protein-
 
Retained intron
---TSL:3
ERBB2-215ENST00000583391.1465No protein-
 
Retained intron
---TSL:3

Gene-based displays